Sumana Sundaramurthy

This study identifies LEV-11E as the sole essential low molecular weight tropomyosin isoform in C. elegans, critical for pharyngeal muscle function despite not stabilizing thin filaments.

This study shows FHOD-1 and profilin cooperate to stabilize sarcomere Z-lines in C. elegans by promoting actin assembly and preventing muscle deformation during contraction.

This study identifies FHOD-1 as the sole formin required for striated muscle growth and Z-line organization in C. elegans through cell autonomous mechanisms.