Author

R. Guan

National Institutes of HealthORCID 0000-0003-2248-4539Unclaimed ORCID profile · follow to get notified of new preprints

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R. Guan8 papers

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 2 Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Research Focus:benchmarking· 1 Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Bing‐Rui ZhouiD· 2 shared Tengfei LianiD· 2 shared Yawen BaiiD· 2 shared

Activity by Year

2023-2024 · peak 1/yr

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3 top collaborators · 3 mutual co-author links

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2 shared papersBiophysics

Bing‐Rui ZhouORCID

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2 papers

Recent·Most cited

BiophysicsNature Structural & Molecular BiologyPeer-reviewedJan 24, 2024

Structural mechanism of synergistic targeting of the CX3CR1 nucleosome by PU.1 and C/EBP

Tengfei Lian, R. Guan, Bing‐Rui Zhou, Yawen Bai

This study reveals how PU.1 and C/EBP synergistically target the CX3CR1 nucleosome by altering DNA positioning and displacing H1 to open chromatin.

28 citations

𝕏 PostBluesky

BiochemistrybioRxivPreprintOct 6, 2023

The human LIN28B nucleosome is inherently pre-positioned for efficient binding of multiple OCT4s without H3 K27 acetylation

Tengfei Lian, R. Guan, Bing‐Rui Zhou, Yawen Bai

This study compares two studies on OCT4 and LIN28B nucleosome interactions, finding that nucleosome positioning and H3 K27 acetylation do not significantly affect OCT4 binding.

7 citations

𝕏 PostBluesky