R. Guan

Emergent survival and extinction of species within gut bacterial communities

The paper shows how species in gut bacterial communities can survive or go extinct based on resource availability and metabolic interactions, identifying emergent survival and community-driven extinctions.

The human LIN28B nucleosome is inherently pre-positioned for efficient binding of multiple OCT4s without H3 K27 acetylation

This study compares two studies on OCT4 and LIN28B nucleosome interactions, finding that nucleosome positioning and H3 K27 acetylation do not significantly affect OCT4 binding.

Neutralization Escape by SARS-CoV-2 Omicron Subvariant BA.2.86

This study evaluates the neutralization escape of the SARS-CoV-2 Omicron subvariant BA.2.86 compared to other variants, finding lower neutralization by antibodies than BA.2 but comparable to circulating variants.

Structural mechanism of synergistic targeting of the CX3CR1 nucleosome by PU.1 and C/EBP

This study reveals how PU.1 and C/EBP synergistically target the CX3CR1 nucleosome by altering DNA positioning and displacing H1 to open chromatin.

Gut microbiome remains stable following COVID-19 vaccination in healthy and immuno-compromised individuals

This study shows that the gut microbiome remains stable after COVID-19 vaccination in both healthy and immuno-compromised individuals, with no significant changes in diversity, phylum, species, or functional capacity.

Structural mechanism of LIN28B nucleosome targeting by OCT4 for pluripotency

This study determines the structural mechanism by which OCT4 targets the LIN28B nucleosome through multivalent interactions, DNA unwrapping, and H1 eviction to initiate cell reprogramming.

Tryptophan specialized metabolism and ER body-resident myrosinases modulate root microbiota assembly

This study shows that ER body-resident myrosinases and Trp metabolism shape root microbiota by secreting bioactive metabolites into the rhizosphere.

GmSALT3 expression improves reactive oxygen species detoxification in salt-stressed soybean roots

The paper uses RNA-seq to show that GmSALT3 improves ROS detoxification in salt-stressed soybean roots by enhancing antioxidant activity and related pathways.

Characterization of the Chlamydomonas reinhardtii phycosphere reveals conserved features of the plant microbiota

The paper characterizes the microbiota of Chlamydomonas reinhardtii's phycosphere and finds it shares taxonomic and functional features with plant root microbiota.

Host preference and invasiveness of commensals in the Lotus and Arabidopsis root microbiota

The paper investigates host preference and invasiveness of commensal bacteria in the root microbiota of Lotus and Arabidopsis, showing host-specific adaptation and competitive advantages.

GmSALT3 confers shoot Na+ and Cl- exclusion in soybean via two distinct processes.

This study identifies GmSALT3 as a functional ion transporter in soybean that improves salt tolerance by enabling root-based Na+ xylem exclusion and shoot-based Cl- exclusion via phloem recirculation.

Super-Resolution Tracking of Mitochondrial Dynamics with An Iridium(III) Luminophore

The paper develops an iridium(III) dye for tracking mitochondrial dynamics under structured illumination microscopy, revealing new insights into mitochondria-lysosome interactions.

Comparison of antioxidant activity between cyanidin-3-O-glucoside (C3G) liposome and cyanidin-3-O-glucoside (C3G) in 2D and 3D cell cultures

This study compares the antioxidant activity of C3G and C3G liposomes in 2D and 3D cell cultures, finding greater effects in the 3D model.