Author

Ishita Sarkar

Indian Institute of Chemical BiologyORCID 0000-0003-2253-2385Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Approach:mechanistic / dynamical model· 1 Organism:mouse· 1

Frequent Co-Authors

Puspendu GhoshiD· 2 shared Sandip PauliD· 2 shared Shaun MahantiiD· 2 shared Shilpak ChatterjeeiD· 2 shared Anupam GautamiD· 1 shared Anupam Goutam· 1 shared Anwesha KariD· 1 shared Anwesha MandaliD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersImmunology

Puspendu GhoshORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintSep 16, 2026

Discovery of a Small-Molecule mTORC1 Pathway Activator that Enhances Adoptive T-Cell Therapy via Immuno-metabolic Reprogramming of CD8+ T Cells

Dipika Sarkar, Puspendu Ghosh, Sunny Goon…·Arindam Talukdar

This paper identifies AS-3, a small-molecule activator of mTORC1 that enhances CD8 T cell function and antitumor efficacy in adoptive cell therapy.

DOI 10.64898/2026.09.11.750909

humanproteomics

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ImmunologybioRxivPreprintJan 6, 2026

Mettl3-catalyzed m6A methylation determines CD8+ T cell differentiation fate in tumor

Puspendu Ghosh, Anupam Gautam, Debashree Basak…·Shilpak Chatterjee

This study identifies Mettl3-m6A methylation as a regulator of CD8+ T cell differentiation fate in tumors, showing its role in promoting terminal exhaustion and its potential as a target to enhance immunotherapy.

DOI 10.64898/2026.01.06.697843

𝕏 PostBluesky