Shilpak Chatterjee

This paper identifies AS-3, a small-molecule activator of mTORC1 that enhances CD8 T cell function and antitumor efficacy in adoptive cell therapy.

This study presents whole-genome and transcriptome analyses of breast tumors from India, identifying novel mutations, copy number alterations, and subtypes with clinical implications.

This study identifies Mettl3-m6A methylation as a regulator of CD8+ T cell differentiation fate in tumors, showing its role in promoting terminal exhaustion and its potential as a target to enhance immunotherapy.