Zane Koch

This paper introduces an AI system for automated small molecule structure elucidation from NMR spectra, combining generative models with reasoning agents to outperform existing tools.

This study shows that DREAM complex activity influences somatic mutation burden, lifespan, and age-related disease, with reduced activity linked to longer lifespan and lower disease risk.

The paper shows that somatic mutations correlate with methylation changes and can predict age similarly to epigenetic clocks.

CSREP summarizes chromatin state annotations within sample groups and identifies differential annotations across groups using probabilistic modeling and logistic regression.