Author

Karl Sperling

Charité – Universitätsmedizin BerlinORCID 0000-0003-2305-4370Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:statistical model· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Alexej KnausiD· 1 shared Dieter BeuleiD· 1 shared Eva Seemanova· 1 shared Fabian BrandiD· 1 shared George Larry MaxwelliD· 1 shared Hannah KlinkhammeriD· 1 shared Heidemarie Neitzel· 1 shared Ilja DemuthiD· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

Alexej KnausORCID

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2 papers

Recent·Most cited

Genetic & Genomic MedicinemedRxivPreprintNov 20, 2023

A transgenerational mutational signature from ionizing radiation exposure.

Fabian Brand, Hannah Klinkhammer, Alexej Knaus…·Peter Michael Krawitz

This study finds that paternal exposure to ionizing radiation increases clustered de novo mutations in offspring, suggesting cDNMs as a transgenerational biomarker.

1 citation

humanwhole-genome sequencing

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Cancer BiologybioRxivPreprintMar 7, 2019

Nijmegen Breakage Syndrome (NBS) is a telomeropathy: analysis of telomere length in NBS homo- and heterozygotes and humanized Nbs ice

Raneem Habib, Ryong Kim, Heidemarie Neitzel…·Michael Walter

This study shows that Nijmegen Breakage Syndrome (NBS) is a telomeropathy, with reduced telomere length in patients, and explores its dual role in cancer susceptibility and survival.

DOI 10.1101/571026

humanbulk RNA-seq

𝕏 PostBluesky