Author

Heath O’Brien

Cardiff UniversityORCID 0000-0003-2309-8736Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Genomics· 2 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1

Frequent Co-Authors

Michael C. O’DonovaniD· 2 shared Nicholas J. BrayiD· 2 shared Richard AnneyiD· 2 shared Aaron R. JeffriesiD· 1 shared Abdou MousasiD· 1 shared Abigail Miller· 1 shared Alexis Rodriguez· 1 shared Alicia Huerta‐ChagoyaiD· 1 shared

Activity by Year

2019-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersGenomics

Michael C. O’DonovanORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Genetic & Genomic MedicineNature GeneticsPeer-reviewedMay 21, 2025

Genome-wide Association Study of Long COVID

Vilma Lammi, Tomoko Nakanishi, Samuel E. Jones…·Sergi Papiol

This study performs a genome-wide association study for Long COVID, identifying a significant association with the FOXP4 locus and highlighting the role of pulmonary dysfunction and COVID-19 severity.

86 citationstop 1%

humanGWAS summary statistics

𝕏 PostBluesky

GenomicsBiological PsychiatryPeer-reviewedMay 10, 2019

Novel Insight into the Aetiology of Autism Spectrum Disorder Gained by Integrating Expression Data with Genome-wide Association Statistics

Oliver Pain, Andrew J. Pocklington, Peter Holmans…·Richard Anney

This study integrates ASD GWAS summary statistics with gene expression data to identify differentially expressed genes in ASD and estimate heritability explained by predicted expression.

80 citationstop 2%

humanbulk RNA-seq

𝕏 PostBluesky

GenomicsbioRxivPreprintMar 21, 2019

Sex differences in gene expression in the human fetal brain

Heath O’Brien, Eilis J. Hannon, Aaron R. Jeffries…·Nicholas J. Bray

The paper analyzes RNA sequencing data from human fetal brains to identify sex-biased gene expression, finding differences in 2558 autosomal and 155 X-chromosome genes, with implications for neurodevelopmental disorders.

22 citations

humanbulk RNA-seq

𝕏 PostBluesky