Nada Kuk

This study shows that MLP1, a nuclear pore complex protein in Trypanosoma brucei, is essential for nuclear integrity, mRNA export, and genome stability by maintaining proper chromosome segregation and ploidy.

The paper identifies a Leishmania infantum strain suitable for genetic studies and provides its genome sequence and CRISPR-Cas9 tools for visceral leishmaniasis research.

The paper uses high throughput single-cell genome sequencing to study mosaic aneuploidy in Leishmania donovani, finding rapid karyotype changes and chromosome-specific adaptations.

This paper uses high-throughput single-cell genome sequencing to analyze karyotype variation in a clonal Leishmania donovani population, revealing mosaic aneuploidy and its potential adaptive role.