ImmunologyNature CommunicationsPeer-reviewed
Inadequate structural constraint on Fab approach rather than paratope elicitation limits HIV-1 MPER vaccine utility
Kemin Tan, Junjian Chen, Yu Kaku…·Mikyung Kim
The paper shows that HIV-1 MPER-targeting antibodies generated by vaccines lack structural constraints needed to access the MPER, despite having bnAb-like paratopes.
6 citations