Author

Shay Leary

Murdoch UniversityORCID 0000-0002-6966-2294Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Research Focus:benchmarking· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Benjamin B. LindseyiD· 2 shared Dennis Y.Q. WangiD· 2 shared Joe HefferiD· 2 shared Katie Johnson· 2 shared Luke R. GreeniD· 2 shared Matthew D. ParkeriD· 2 shared Mohammad RazaiD· 2 shared Silvana GaudieriiD· 2 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBioinformatics

Benjamin B. LindseyORCID

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2 papers

Recent·Most cited

periscope: Sub-Genomic RNA Identification in SARS-CoV-2 Genomic Sequencing Data

Matthew D. Parker, Benjamin B. Lindsey, Shay Leary, Silvana Gaudieri, Abha Chopra, Matthew Wyles, Adrienn Angyal, Luke R. Green, Paul Parsons, Rachel M Tucker, Rebecca Brown, Danielle Groves, Katie Johnson, Laura Carrilero, Joe Heffer, , Thushan I. de Silva

Periscope identifies and quantifies sub-genomic RNAs in SARS-CoV-2 genomic data, detecting canonical and non-canonical sgRNAs with high fidelity.

Genome Research · Apr 1, 2021Peer-reviewedBioinformatics

Altered Subgenomic RNA Expression in SARS-CoV-2 B.1.1.7 Infections

Matthew D. Parker, Benjamin B. Lindsey, Dhruv R. Shah, Sharon Nienyun Hsu, Alexander James Keeley, David George Partridge, Shay Leary, Alison Cope, Amy State, Katie Johnson, Nasar Ali, Rasha Raghei, Joe Heffer, Darren Smith, Peijun Zhang, , Thushan I. de Silva

The paper shows that B.1.1.7 SARS-CoV-2 lineage has increased subgenomic RNA expression compared to other lineages, with a noncanonical sgRNA near ORF9b showing a 16-fold increase in median expression.

bioRxiv · Mar 2, 2021 · PreprintGenomics