Andrés Binolfi

This study identifies STARD3 as a non-vesicular cholesterol transporter in C. elegans, showing its structural and functional role in sterol mobilization and genetic interaction with the NPC1/NPC2 pathway.

The paper develops a system to reversibly control UFA biosynthesis in C. elegans by targeting fat-7 while deleting fat-5 and fat-6, revealing its essential role in early development and lipid metabolism.

The paper identifies genetic variations in G-quadruplex forming sequences that affect transcription of disease-related genes and may contribute to disease susceptibility.

The paper shows that G-quadruplexes in pre-miR-150 regulate miRNA biogenesis in zebrafish embryos by competing with the stem-loop structure.