Mónica P. Colaiácovo

Genetic and physical interactions reveal overlapping and distinct contributions to meiotic double-strand break formation in C. elegans

The paper investigates genetic and physical interactions of DSB factors in C. elegans, revealing HIM-5's role in X-chromosome-specific crossovers and its dependency on DSB-1.

Unsaturated Fatty Acids Are Required for Germline Proliferation and Membrane Structural Integrity in Caenorhabditis elegans

This study shows that unsaturated fatty acids are essential for germline proliferation, DNA replication, meiotic progression, and membrane integrity in C. elegans.

An inducible and reversible system to regulate unsaturated fatty acid biosynthesis in C. elegans

The paper develops a system to reversibly control UFA biosynthesis in C. elegans by targeting fat-7 while deleting fat-5 and fat-6, revealing its essential role in early development and lipid metabolism.

Germline mitotic quiescence and programmed cell death are induced in C. elegans by exposure to pathogenic P. aeruginosa

This study shows that exposure to P. aeruginosa in C. elegans reduces brood size by inducing programmed germ cell death and mitotic quiescence, which are reversible upon removal of the pathogen.

CRTC-1 Balances Histone Trimethylation and Acetylation to Promote Longevity

This study identifies CRTC-1's role in balancing histone trimethylation and acetylation to promote longevity in C. elegans.

The tumor suppressor BRCA1/BARD1 complex localizes to the synaptonemal complex and regulates recombination under meiotic dysfunction in Caenorhabditis elegans

Fanconi Anemia FANCM/FNCM-1 and FANCD2/FCD-2 are required for maintaining histone methylation levels and interact with the histone demethylase LSD1/SPR-5 in C. elegans

This study shows that LSD1/CeSPR-5 interacts with FANCM/CeFNCM-1 and FANCD2/CeFCD-2 in C. elegans, and the FA pathway maintains H3K4me2 levels during DNA repair.