Layer V Neocortical Neurons From Individuals With Drug-Resistant Epilepsy Show Multiple Synaptic Alterations but Lack Somatic Hyperexcitability
Luis Alfredo Márquez, Christopher Martínez-Aguirre, Estefanía Gutiérrez-Castañeda…·Emilio J. Galván
The paper examines synaptic and electrophysiological properties of layer V pyramidal neurons in drug-resistant epilepsy patients, finding synaptic alterations rather than somatic hyperexcitability contribute to seizure activity.