Author

Linlin M. Chen

Broad InstituteORCID 0000-0003-2401-2420Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:scRNA-seq· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Organism:mouse· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Fei CheniD· 3 shared Samuel G. RodriquesiD· 3 shared Aleksandrina GoevaiD· 1 shared Anna GrekaiD· 1 shared Benjamin R. DoughtyiD· 1 shared Caroline MartiniD· 1 shared Charles P. FulcoiD· 1 shared Charles R. VanderburgiD· 1 shared

Activity by Year

2019-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersGenomics

Fei ChenORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

GenomicsProceedings of the National Academy of SciencesPeer-reviewedDec 21, 2020

HyPR-seq: Single-cell quantification of chosen RNAs via hybridization and sequencing of DNA probes

Jamie L. Marshall, Benjamin R. Doughty, Vidya Subramanian…·J Engreitz

HyPR-seq sensitively quantifies up to 100 chosen genes in single cells, achieving high sensitivity for individual transcripts and reducing costs compared to whole-transcriptome scRNA-seq.

36 citations

scRNA-seqexperimental assay

𝕏 PostBluesky

Synthetic BiologybioRxivPreprintFeb 8, 2020

Recording the age of RNA with deamination

Samuel G. Rodriques, Linlin M. Chen, Sophia Liu…·Fei Chen

This paper introduces RNA timestamps to infer RNA age using A-to-I editing, enabling temporal analysis of gene expression in single-cell RNA sequencing.

2 citations

scRNA-seqstatistical model

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GenomicsSciencePeer-reviewedMar 28, 2019

Slide-seq: A Scalable Technology for Measuring Genome-Wide Expression at High Spatial Resolution

Samuel G. Rodriques, Robert R. Stickels, Aleksandrina Goeva…·Evan Z. Macosko

Slide-seq measures genome-wide expression in complex tissues at 10-micron resolution.

2,425 citationstop 1%

mousespatial transcriptomics

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