Molecular BiologybioRxivPreprint
N-glycosylation blocks and simultaneously fosters different receptor-ligand binding sites: the chameleonic CD44-hyaluronan interaction
Joni Vuorio, Jana Škerlová, Milan Fábry…·Hector Martinez‐Seara
This study shows how N-glycosylation modulates CD44's binding to hyaluronan by altering binding site affinity and promoting weaker interactions.