Cancer BiologybioRxivPreprint
In silico reconstruction of primary and metastatic tumor architecture using GIS-augmented spatial transcriptomics
Jin Young Yoo, Sabrina Akter, Qianying Zuo…·Zeynep Madak‐Erdogan
This paper introduces GIS-ROTA, a framework that integrates biological knowledge with spatial transcriptomics to identify functionally relevant spatial domains in breast tumors.
DOI 10.1101/2025.10.16.682879