Debapriya Dutta

This study identifies novel 17β-hydroxysteroid dehydrogenases in Peptoniphilus and Anaerococcus that convert androstenedione to testosterone, expanding understanding of microbial androgen metabolism in the genitourinary tract.

This study identifies ACSS2-mediated metabolic-epigenetic crosstalk as a driver of Fulvestrant resistance in ER+ breast cancer and presents ACSI as a potential therapeutic target.

The study identifies Actinobaculum massiliense as a urinary pathobiont capable of generating androgens via the dirAB pathway, using a novel HSDH assay.

This paper introduces GIS-ROTA, a framework that integrates biological knowledge with spatial transcriptomics to identify functionally relevant spatial domains in breast tumors.

This study identifies a bacterial pathway for androgen production, showing that gut and urinary bacteria can convert androstenedione to epitestosterone and testosterone, which promote prostate cancer growth.