Author

Audrey Lam

Carle Foundation Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Research Focus:spatial domain detection· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Betsy Barnick· 2 shared Debapriya DuttaiD· 2 shared Jin Young YooiD· 2 shared Mahima GoeliD· 2 shared Zeynep Madak‐ErdoganiD· 2 shared Aiman SolimaniD· 1 shared Alexander MichelsiD· 1 shared Alicia Arredondo EveiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCancer Biology

Betsy Barnick

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3 papers

Recent·Most cited

NanoPro - a Framework for Probiotically-Guided Nanovector Therapy

Alexander Michels, Azra Haseki, Myra Ashraf, Audrey Lam, Kailyn R Grant, Amy Lu, Rosa L. Vincent, Jongwon Im, Zakary S. Singer, Edward R. Ballister, Tal Danino

The paper introduces NanoPro, a nanovector therapy platform using probiotically-released tumor-binding tags to target antigenically indistinct tumors, demonstrating in vitro efficacy with high transduction rates.

bioRxiv · Oct 29, 2026 · PreprintSynthetic Biology

ACSS2-Mediated Metabolic-Epigenetic Crosstalk Drives Fulvestrant Resistance and Represents a Novel Therapeutic Target

Ayca Nazli Mogol, Jin Young Yoo, Alicia Arredondo Eve, Mahima Goel, David J Dutton, Claire P. Schane, Audrey Lam, Debapriya Dutta, Betsy Barnick, Eda D. Erdogan, Erik Russell Nelson, Maria Grosse-Perdekamp, Zeynep Madak‐Erdogan

This study identifies ACSS2-mediated metabolic-epigenetic crosstalk as a driver of Fulvestrant resistance in ER+ breast cancer and presents ACSI as a potential therapeutic target.

npj Breast Cancer · Jun 27, 2026Peer-reviewedCancer Biology

In silico reconstruction of primary and metastatic tumor architecture using GIS-augmented spatial transcriptomics

Jin Young Yoo, Sabrina Akter, Qianying Zuo, Amir Kazemi, Wenjun Wu, Mahima Goel, Audrey Lam, Debapriya Dutta, Betsy Barnick, Melike Pekmezci, Maria Grosse Perdekamp, Aiman Soliman, Zeynep Madak‐Erdogan

This paper introduces GIS-ROTA, a framework that integrates biological knowledge with spatial transcriptomics to identify functionally relevant spatial domains in breast tumors.

bioRxiv · Oct 16, 2025 · PreprintCancer Biology