Savandara Besse

This study shows that telomerase deficiency in zebrafish accelerates brain ageing by promoting senescence, inflammation, and blood-brain barrier dysfunction.

The paper maps genetic variation's effect on protein-protein interactions in yeast, finding trans-acting SNPs have larger effects than cis-acting ones and SNPs in non-coding regions are significant.

The paper introduces a two-phase model of ageing using Smurfness to distinguish chronological age effects from biological age effects in transcriptional data.

The paper compares protein aggregation propensity and mutation tolerance between naked mole-rat and mouse orthologous proteins, finding significant differences in specific protein subsets related to aging processes.