Author

Céline Cansell

AgroParisTechORCID 0000-0002-9579-5250Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Neuroscience· 2 Physiology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:mouse· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Carole RovèreiD· 3 shared Clara SancheziD· 2 shared Flaminia ZaneiD· 2 shared Michaël ReraiD· 2 shared Nicolas ToddiD· 2 shared Alexandre BénaniiD· 1 shared CA. Mosser· 1 shared Christophe AntoniewskiiD· 1 shared

Activity by Year

2019-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersNeuroscience

Carole RovèreORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

"Smurf Mice": revolutionising our understanding of age-related and end-of-life animal physiology

Céline Cansell, Vivien Goepp, Fanny Bain, Nicolas Todd, Véronique Douard, Magali Monnoye, Flaminia Zane, Clara Sanchez, Nicolas Pietrancosta, Carole Rovère, R Denis, Serge H. Luquet, Michaël Rera

This paper validates a two-phase ageing model in mice, showing a phenotypic signature of imminent death across chronological ages.

bioRxiv · Jun 14, 2025 · PreprintPhysiology

Computational detection, characterization, and clustering of microglial cells in a mouse model of fat-induced postprandial hypothalamic inflammation

Clara Sanchez, Morgane Nadal, Céline Cansell, Sarah Laroui, Xavier Descombes, Carole Rovère, Éric Debreuve

This paper introduces an automated algorithm to detect and cluster microglial cells in mouse hypothalamic tissue, revealing morphological subpopulations affected by high-fat diet.

Methods · Feb 26, 2025Peer-reviewedNeuroscience

Smurfness-based two-phase model of ageing helps deconvolve the ageing transcriptional signature

Flaminia Zane, Hayet Bouzid, Sofia Sosa Marmol, Mira Brazane, Savandara Besse, Julia Lisa Molina, Céline Cansell, Fanny Aprahamian, Sylvère Durand, Jessica Ayache, Christophe Antoniewski, Nicolas Todd, Clément Carré, Michaël Rera

The paper introduces a two-phase model of ageing using Smurfness to distinguish chronological age effects from biological age effects in transcriptional data.

Aging Cell · Oct 12, 2023Peer-reviewedSystems Biology

Fat food exacerbates post-prandial hypothalamic inflammation involving GFAP+ cells and microglia

Céline Cansell, Katharina Stobbe, Ophélia Le Thuc, CA. Mosser, Selma Ben Fradj, Joris Leredde, Cynthia Lebeaupin, Delphine Debayle, Lucile Fleuriot, Frédéric Brau, Nadège Devaux, Alexandre Bénani, Étienne Audinat, Nicolas Blondeau, Jean‐Louis Nahon, Carole Rovère

The paper investigates how high-fat diet exposure increases hypothalamic inflammation and glial cell activity in mice, linking it to potential obesity risk.

bioRxiv · Nov 12, 2019 · PreprintNeuroscience