Hongwei Zhou

This study identifies indole-3-propionic acid (IPA) as a gut microbiota-derived metabolite that prevents post-stroke cognitive impairment by preserving catecholamines in the dorsal hippocampus.

The paper presents a comprehensive compendium of fully circularized human gut bacterial genomes and reveals how mobile genetic elements drive functional diversity with therapeutic implications.

RIM-Deep improves deep imaging of cleared brain tissue in inverted confocal microscopy, extending imaging depth from 2 mm to 5 mm in cleared macaque and mouse brains.

This study identifies food pairing patterns linked to cardiometabolic traits across populations, showing their independent association beyond single-food effects and dietary indices.

MOBFinder classifies plasmid metagenomic fragments into MOB categories using natural language models, achieving higher accuracy than existing tools.

DeePVP improves PVP identification and classification using deep learning, achieving higher accuracy than existing tools in both tasks.

The paper characterizes the vaginal microbiome and sialidase activity in 2689 Chinese pregnant women, finding no association with preterm birth risk.