Author

Matteo Doglio

IRCCS Ospedale San RaffaeleORCID 0000-0003-2477-2139Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Organism:human· 1

Frequent Co-Authors

Chiara BoniniiD· 2 shared Aesha Vakil· 1 shared Alaina Burgess· 1 shared Alberto Del Río-EspínolaiD· 1 shared Alessia UgoliniiD· 1 shared Alice Calderoni· 1 shared Annaiz Grimm· 1 shared Brock McKinney· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersImmunology

Chiara BoniniORCID

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2 papers

Recent·Most cited

CD19 CAR Engineered T Regulatory Cells Promote Durable Immune Tolerance in Experimental Systemic Lupus Erythematosus

Travis Drow, Matteo Doglio, Annaiz Grimm, Victoria DeVault-Nelson, Maegan Hoover, Brock McKinney, Subhash Kumar Tripathi, Jennifer Mellen, Madison Milazewski, Payam Zarin, Alaina Burgess, Christopher L. Moore, Pierluigi Carulli, Alessia Ugolini, Clara Bercher, , David J. Rawlings

This study shows that CD19 CAR-engineered regulatory T cells reduce B cell numbers, inflammation, and autoantibodies in lupus models, promoting long-term immune tolerance.

bioRxiv · Oct 11, 2026 · PreprintImmunology

Engineered α-Synuclein-specific nanobody CAR iTregs restrain neuroinflammation and proteinopathy in Parkinson's disease mice

Alice Calderoni, Melania Nannoni, Giorgia Ruffini, Matteo Doglio, Clara Bercher-Brayer, Serena Gea Giannelli, Ronald Melki, Monica Casucci, Chiara Bonini, Sharon Muggeo, Vania Broccoli

This study develops Syn-specific CAR iTregs that reduce neuroinflammation and proteinopathy in PD mice by selectively targeting aggregated α-Synuclein.

bioRxiv · Aug 22, 2026 · PreprintNeuroscience