Johann du Hoffmann

This study investigates how α7-nicotinic cholinergic receptors affect perceptual sensitivity in a visual signal detection task, finding dose-dependent improvements with antagonists and impairments with agonists and modulators.

This study shows that GABRA5 expression in the prelimbic cortex correlates with visual perceptual learning speed and that a GABRA5 modulator improves learning in poor performers.

This study identifies Auxilin mutations as a cause of Parkinson's disease by showing they impair clathrin-mediated trafficking at the Golgi and synapse, leading to neuropathological lesions.