Developmental BiologybioRxivPreprint
Human Pluripotent Stem Cell Derived Organoids Reveal a Role for WNT Signaling in Dorsal-Ventral Patterning of the Hindgut
Na Qu, Abdelkader Daoud, Daniel O. Kechele, Jorge O. Múnera
This study uses human pluripotent stem cell-derived hindgut cultures to show that WNT signaling directs dorsal-ventral patterning, promoting urothelial fate over colorectal fate.