Abdelkader Daoud

NEUROG3 Is Sufficient to Drive Neuroendocrine Differentiation in Prostate Cancer Cells.

This study shows NEUROG3 can drive neuroendocrine differentiation in prostate cancer cells, identifying it as a potential mediator of cancer progression.

A technique for evaluating calcium flux in primary airway tissue at single cell resolution

The paper develops a method to study calcium flux in primary human airway tissue at single-cell resolution using live imaging and machine learning analysis.

Benchmarking organ-specific responses to therapies in tissues differentiated from Cystic Fibrosis patient derived iPSCs

This study benchmarks Trikafta's efficacy in CF patient-derived iPSC-derived colonic and airway tissues compared to isogenic controls, showing differential therapeutic responses.

Human Pluripotent Stem Cell Derived Organoids Reveal a Role for WNT Signaling in Dorsal-Ventral Patterning of the Hindgut

This study uses human pluripotent stem cell-derived hindgut cultures to show that WNT signaling directs dorsal-ventral patterning, promoting urothelial fate over colorectal fate.