Author

Alessio D’Addabbo

University of SouthamptonORCID 0000-0003-2542-6465Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Alyssa ThomasiD· 1 shared Emma T CrooksiD· 1 shared James Μ. BinleyiD· 1 shared Jiamin XuiD· 1 shared Joel D. AlleniD· 1 shared Keiko OsawaiD· 1 shared Max CrispiniD· 1 shared Tommy TongiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperImmunology

Alyssa ThomasORCID

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1 paper

Recent·Most cited

ImmunologyGlycobiologyPeer-reviewedAug 7, 2024

Impact of Glycan Depletion, Glycan Debranching and Increased Glycan Charge on HIV-1 Neutralization Sensitivity and Immunogenicity

Alessio D’Addabbo, Tommy Tong, Emma T Crooks…·James Μ. Binley

This study evaluates glycoengineered HIV-1 trimers to enhance bNAb recognition, finding that B4GalT1+ST6GalT1 modifications increase antibody titers in infected donors but reduce vaccine-induced neutralizing antibodies.

3 citations

humanproteomics

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