The paper shows that reward-tethered place cells in the hippocampus adjust their activity when reward magnitude changes, enabling flexible coding and remapping while preserving spatial maps.

DOI 10.64898/2026.05.15.725501

mouseimaging

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NeuroscienceNature CommunicationsPeer-reviewedJan 2, 2025

Distinct roles of dentate gyrus and medial entorhinal cortex inputs for phase precession and temporal correlations in hippocampal CA3 place cells

Siavash Ahmadi, Takuya Sasaki, Marta Sabariego…·Jill K. Leutgeb

20 citationstop 2%

statistical model

𝕏 PostBluesky

NeuroscienceHippocampusPeer-reviewedOct 7, 2024

Flexible behavioral adjustment to frustrative nonreward in anticipatory behavior, but not in consummatory behavior, requires the dorsal hippocampus

Christopher W. Hagen, Megi Hoxha, Saee Chitale…·Marta Sabariego

This study investigates the role of the dorsal hippocampus in adjusting anticipatory behavior versus consummatory behavior during reward downshifts in rats, finding it critical for anticipatory adjustments but not consummatory ones.

4 citations

ratexperimental assay

𝕏 PostBluesky