NeuroscienceeLifePeer-reviewed
Genetic dissection of the different roles of hypothalamic kisspeptin neurons in regulating female reproduction
Luhong Wang, Charlotte Vanacker, Laura L. Burger…·Suzanne M. Moenter
This study uses CRISPR-Cas9 to disrupt ER in specific kisspeptin neuron populations in adult mice, revealing distinct roles of AVPV and arcuate kisspeptin neurons in estradiol-mediated negative and positive feedback on GnRH.
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