Developmental BiologybioRxivPreprint
Functional characterization of human Homeodomain-interacting protein kinases (HIPKs) in Drosophila melanogaster reveal both conserved functions and differential induction of HOX gene expression
Stephen D. Kinsey, Gerald A. Shipman, Esther M. Verheyen
The paper uses Drosophila to study human HIPKs, finding that hHIPK1 and hHIPK2 can rescue lethality, while hHIPK3 and hHIPK4 only rescue minor defects, and that HIPKs inhibit Polycomb-group complex activity.
DOI 10.1101/2020.11.03.366393