Mohammed Khaled

The paper investigates the conformational landscape of a SMN2 splice-site defect using molecular dynamics simulations and shows that solvation models significantly affect the equilibrium between different conformations.

The paper maps the conformational landscape of TRMT2A RRM using molecular dynamics and identifies a hydrophobic cluster that governs allostery and RNA recognition.

The paper investigates how anion-protein interactions influence insulin phase separation and amyloid formation through H-bonds and electrostatics, revealing alternative pathways to fibril formation.