Gabriella Rita Pangilinan

This study shows that sympathetic aging is reversible and sexually dimorphic, with male mice showing greater denervation due to gonadal influences and target environment changes.

The paper generates a collection of 65 isogenic human stem cell lines with PD-associated mutations to study Parkinson's disease, revealing that most genetic variation comes from cell culture rather than genome editing.

This paper compares prime editing efficiency to conventional methods in human pluripotent stem cells, showing higher efficiency with optimized mRNA delivery for mutation correction and introduction.