Author

Wim J. Mandemakers

Erasmus MCORCID 0000-0003-2673-5972Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:differential expression· 3 Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Assay:imaging· 1 Assay:proteomics· 1

Frequent Co-Authors

Vincenzo BonifatiiD· 4 shared Ana Carreras MascaroiD· 3 shared Federico FerraroiD· 3 shared Guido J. BreedveldiD· 3 shared Valerie Boumeester· 3 shared Frank Jan de JongiD· 2 shared Leonie J.M. VergouwiD· 2 shared Martyna M. GrochowskaiD· 2 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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4 shared papersNeuroscience

Vincenzo BonifatiORCID

Mutual co-authors in cluster

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4 papers

Recent·Most cited

NeurosciencebioRxivPreprintNov 28, 2023

Interactome mapping reveals a role for LRP10 in autophagy and NDFIP1-mediated alpha-synuclein secretion

Ana Carreras Mascaro, Federico Ferraro, Valerie Boumeester…·Wim J. Mandemakers

This study identifies LRP10 interactors and pathways, showing its role in autophagy and NDFIP1-mediated alpha-synuclein secretion, with differences between LRP10-WT and LRP10-Splice variants.

DOI 10.1101/2023.11.28.569009

humanproteomics

𝕏 PostBluesky

NeurosciencebioRxivPreprintMay 12, 2023

LRP10 as a novel α-synuclein regulator in Lewy body diseases

Ana Carreras Mascaro, Martyna M. Grochowska, Valerie Boumeester…·Wim J. Mandemakers

This study investigates the role of LRP10 in Lewy body diseases, showing it regulates α-synuclein levels and interacts with a disease-associated variant.

1 citation

humanexperimental assay

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NeurosciencebioRxivPreprintNov 8, 2022

deCLUTTER2+ pipeline to analyze calcium traces in a novel stem cell model for ventral midbrain patterned astrocytes

Martyna M. Grochowska, Federico Ferraro, Ana Carreras Mascaro…·Wim J. Mandemakers

The paper introduces a new pipeline for analyzing calcium traces in a stem cell model of ventral midbrain astrocytes, enabling functional characterization under physiological and PD conditions.

DOI 10.1101/2022.11.08.515628

humanimaging

𝕏 PostBluesky

BioinformaticsCellsPeer-reviewedJan 7, 2022

Correcting differential gene expression analysis for cyto-architectural alterations in substantia nigra of Parkinson's disease patients reveals known and potential novel disease-associated genes and pathways

Federico Ferraro, Christina Fevga, Vincenzo Bonifati…·Marcel J. T. Reinders

1 citation

humanbulk RNA-seq

𝕏 PostBluesky