Author

Frank Jan de Jong

Erasmus MCORCID 0000-0002-7267-6806Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:proteomics· 1

Frequent Co-Authors

Ana Carreras MascaroiD· 2 shared Guido J. BreedveldiD· 2 shared Leonie J.M. VergouwiD· 2 shared Valerie Boumeester· 2 shared Vincenzo BonifatiiD· 2 shared Wim J. MandemakersiD· 2 shared Anne‐Marie van DamiD· 1 shared Annemieke J.M. RozemülleriD· 1 shared

Activity by Year

2017-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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2 shared papersNeuroscience

Ana Carreras MascaroORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Interactome mapping reveals a role for LRP10 in autophagy and NDFIP1-mediated alpha-synuclein secretion

Ana Carreras Mascaro, Federico Ferraro, Valerie Boumeester, Guido J. Breedveld, Dick H. W. Dekkers, Leonie J.M. Vergouw, Frank Jan de Jong, Jeroen Demmers, Vincenzo Bonifati, Wim J. Mandemakers

This study identifies LRP10 interactors and pathways, showing its role in autophagy and NDFIP1-mediated alpha-synuclein secretion, with differences between LRP10-WT and LRP10-Splice variants.

bioRxiv · Nov 28, 2023 · PreprintNeuroscience

LRP10 as a novel α-synuclein regulator in Lewy body diseases

Ana Carreras Mascaro, Martyna M. Grochowska, Valerie Boumeester, Natasja F. J. Dits, Ece Naz Bilgiҫ, Guido J. Breedveld, Leonie J.M. Vergouw, Frank Jan de Jong, Martin E. van Royen, Vincenzo Bonifati, Wim J. Mandemakers

This study investigates the role of LRP10 in Lewy body diseases, showing it regulates α-synuclein levels and interacts with a disease-associated variant.

bioRxiv · May 12, 2023 · PreprintNeuroscience

Insular cortex sub-region-dependent distribution pattern of α-synuclein immunoreactivity in Parkinson’s disease and dementia with Lewy bodies

Yasmine Y. Fathy, Frank Jan de Jong, Anne‐Marie van Dam, Annemieke J.M. Rozemüller, Wilma D. J. van de Berg

This study examines the distribution of α-synuclein pathology in insular cortex sub-regions in Parkinson’s disease and dementia with Lewy bodies, revealing regional differences in vulnerability.

bioRxiv · Jun 28, 2017 · PreprintNeuroscience