Aaron D. Mickle

This study shows that urothelial cell signaling via P2X, muscarinic, Ca2+, GPCR, and exocytotic pathways can induce local bladder contractions without central nervous system involvement.

This study shows that ampakines improve bladder voiding and coordination in a rat SCI model by enhancing AMPA receptor function.

The paper presents an open-source hardware and software system for delivering timed pressure distensions in animal models using an Arduino-based solenoid valve controller.

This study uses optogenetic inhibition of Nav1.8+ bladder sensory afferents in a mouse model of cystitis to reduce pain and hypersensitivity.

This study identifies macrophage AT2R activation as a key driver of neuropathic pain through ROS/NO-mediated TRPA1 activation in sensory neurons.