Author

Oscar A. Nyangiri

Makerere UniversityORCID 0000-0003-2741-2921Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 4 Genetic & Genomic Medicine· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 6 Organism:human· 4 Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Research Focus:GWAS / association mapping· 2 Research Focus:fine-mapping· 1 Assay:GWAS summary statistics· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Enock MatovuiD· 6 shared Harry A. NoyesiD· 6 shared Julius MulindwaiD· 6 shared Annette MacLeodiD· 5 shared Barbara NerimaiD· 5 shared Peter NambalaiD· 5 shared Janelisa MusayaiD· 4 shared Joyce NamulondoiD· 4 shared

Activity by Year

2017-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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6 shared papersGenomics

Enock MatovuORCID

Mutual co-authors in cluster

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6 papers

Recent·Most cited

GenomicsbioRxivPreprintSep 7, 2024

GENETIC DIVERSITY OF T. B. RHODESIENSE SERUM RESISTANCE ASSOCIATED GENE IN MALAWIAN ISOLATES

Peter Nambala, Calorine Claucus, Harry A. Noyes…·Julius Mulindwa

The paper investigates the genetic diversity of the SRA gene in T. b. rhodesiense isolates and APOL-1 genotypes in Malawian r-HAT patients, finding heterozygosity in SRA and severe r-HAT cases in APOL-1 G2 individuals.

DOI 10.1101/2024.09.07.611819

statistical model

𝕏 PostBluesky

Genetic & Genomic MedicinemedRxivPreprintMay 14, 2024

A Genome-Wide Association Study Reveals Novel Genetic Markers Associated with Human African Trypanosomiasis

Julius Mulindwa, Magambo Phillip Kimuda, Harry A. Noyes…·Enock Matovu

DOI 10.1101/2024.05.14.24307227

humanGWAS summary statistics

𝕏 PostBluesky

GeneticsPLoS neglected tropical diseasesPeer-reviewedDec 6, 2023

Distinct Differences in Gene Expression Profiles in Early and Late Stage Rhodesiense HAT Individuals in Malawi

Peter Nambala, Julius Mulindwa, Harry A. Noyes…·Janelisa Musaya

This study compares gene expression profiles between early and late stage r-HAT patients in Malawi, identifying differentially expressed genes and potential diagnostic biomarkers.

2 citations

humanbulk RNA-seq

𝕏 PostBluesky

GenomicsbioRxivPreprintJul 11, 2023

Transcriptome profiles of T.b. rhodesiense parasites in Malawi reveal focus specific gene expression Profiles associated with pathology

Peter Nambala, Harry A. Noyes, Joyce Namulondo…·Julius Mulindwa

The paper analyzes transcriptome profiles of T.b. rhodesiense isolates from two Malawi foci, finding focus-specific gene expression patterns linked to disease severity and population structure.

DOI 10.1101/2023.07.11.548495

bulk RNA-seqstatistical model

𝕏 PostBluesky

GenomicsbioRxivPreprintJun 13, 2023

Transcriptome analysis of peripheral blood of Schistosoma mansoni infected children from the Albert Nile region in Uganda reveals genes implicated in fibrosis pathology.

Joyce Namulondo, Oscar A. Nyangiri, Magambo Phillip Kimuda…·Julius Mulindwa

This study analyzes RNA-seq data from Ugandan children infected with Schistosoma mansoni to identify differentially expressed genes associated with infection intensity and fibrosis-related pathways.

DOI 10.1101/2023.06.13.544714

humanbulk RNA-seq

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GenomicsbioRxivPreprintOct 12, 2017

Evidence of population specific selection inferred from 289 genome sequences of Nilo-Saharan and Niger-Congo linguistic groups in Africa

Julius Mulindwa, Harry A. Noyes, Hamidou Ilboudo…·Enock Matovu

The paper analyzes 289 genome sequences from Nilo-Saharan and Niger-Congo populations to identify population-specific selection signatures linked to disease resistance.

2 citations

humanwhole-genome sequencing

𝕏 PostBluesky