Peter Nambala

Effects of different concentrations and combinations of antibiotics on the dynamics of intracellular transposition in Escherichia coli

This study examines how sub-inhibitory concentrations of ceftriaxone, combined with colistin and kanamycin, affect intracellular transposition in Escherichia coli, identifying thresholds for environmental impact.

Covalent Inhibition of New Delhi Metallo-β-Lactamases NDM-1 and NDM-5 by 3-Bromopyruvate

This study shows 3-BP covalently inhibits NDM-1 and NDM-5 MBLs, restoring carbapenem activity against resistant bacterial strains.

GENETIC DIVERSITY OF T. B. RHODESIENSE SERUM RESISTANCE ASSOCIATED GENE IN MALAWIAN ISOLATES

The paper investigates the genetic diversity of the SRA gene in T. b. rhodesiense isolates and APOL-1 genotypes in Malawian r-HAT patients, finding heterozygosity in SRA and severe r-HAT cases in APOL-1 G2 individuals.

A Genome-Wide Association Study Reveals Novel Genetic Markers Associated with Human African Trypanosomiasis

Distinct Differences in Gene Expression Profiles in Early and Late Stage Rhodesiense HAT Individuals in Malawi

This study compares gene expression profiles between early and late stage r-HAT patients in Malawi, identifying differentially expressed genes and potential diagnostic biomarkers.

Transcriptome profiles of T.b. rhodesiense parasites in Malawi reveal focus specific gene expression Profiles associated with pathology

The paper analyzes transcriptome profiles of T.b. rhodesiense isolates from two Malawi foci, finding focus-specific gene expression patterns linked to disease severity and population structure.

Transcriptome analysis of peripheral blood of Schistosoma mansoni infected children from the Albert Nile region in Uganda reveals genes implicated in fibrosis pathology.

This study analyzes RNA-seq data from Ugandan children infected with Schistosoma mansoni to identify differentially expressed genes associated with infection intensity and fibrosis-related pathways.