Connor J. Maltby

The paper investigates RAN translation from HTT CAG repeats, showing it occurs in multiple reading frames without AUG start codons and is detectable in neurons.

This study shows that AAGGG repeat expansions cause synaptic defects in CANVAS neurons independently of RFC1, with phenotypes corrected by repeat deletion.

This study identifies a G-quadruplex in the 5' UTR of KCNK9 mRNA that regulates its localization and translation, affecting potassium leak currents in neurons.