Aymeric Silvin

This study develops a syngeneic mouse model of MSI cancer and shows that immune responses regulate metastasis in MSI-H tumors, with specific immune cell infiltration observed in metastatic sites.

This study shows that Ermin deficiency causes myelin abnormalities and inflammation, leading to neurological deficits and increased susceptibility to demyelination, suggesting it as an 'inside-out' model for inflammatory dysmyelination.