Tapsi Kumar

This paper constructs a comprehensive spatially resolved single-cell genomic atlas of the adult human breast, identifying 11 major cell types and revealing diverse immune and epithelial cell populations.

The paper uses genomic profiling to show that some invasive breast cancers are clonally unrelated to their preceding DCIS, suggesting DCIS may act as both a precursor and independent risk factor.

SCMarker identifies cell-type-discriminative markers in scRNA-seq data through unsupervised analysis of gene expression patterns without prior knowledge.