Michael T. Roberts

This study investigates how neurons in the inferior colliculus encode frequency-modulated sound features using multiplexing strategies, finding that temporal coding and combinatorial representations are key.

This study maps T-stellate neuron connectivity and synaptic physiology to IC neurons using optogenetics and electrophysiology, revealing differences in input strength and plasticity between NPY and VIP neurons.

This study models how heminode disruption in spiral ganglion neurons interacts with background noise to impair auditory processing and sound localization.

This paper introduces CytoTape, a tool for continuous, multiplexed recording of gene regulation dynamics over weeks at single-cell resolution, and demonstrates its use in measuring transcription factor activities.

This study identifies a ventral tectal longitudinal column in mice with extensive auditory connections, similar to findings in rats.

This paper investigates the role of GluN2C/D-containing NMDA receptors in the inferior colliculus, showing they enhance temporal summation and affect firing rates in response to sound.

The paper uses lineage-tracing to identify a larger population of NPY neurons in the inferior colliculus and shows they provide inhibitory input to local circuits.

The paper shows that NPY signaling regulates recurrent excitation in the auditory midbrain by modulating Y1R+ neuron activity and synaptic plasticity.

The paper shows cholinergic boutons contact VIP neurons in the inferior colliculus, influencing their synaptic computations.

The paper investigates the commissural projections of NPY neurons in the inferior colliculus, finding they exhibit a divergent and heterotopic pattern compared to non-NPY neurons.

This study shows that 3β4* nAChRs strongly excite VIP neurons in the mouse inferior colliculus, influencing auditory processing through prolonged excitability.

The paper identifies a novel class of GABAergic projection neurons in the inferior colliculus expressing neuropeptide Y and shows they regulate circuit excitability through NPY and GABA signaling.

This paper introduces a method using channelrhodopsin-assisted circuit mapping to precisely map long-range auditory projections in the brainstem with blue and red-shifted opsins.

The paper identifies VIP neurons in the mouse inferior colliculus as a novel class of principal neurons with specific connectivity and functional roles in auditory circuits.