Susumu Tonegawa

This study shows that cingulate cortex inputs to motor cortex are necessary for updating rule representations during sequential choice decisions after rule switches.

The paper maps contextual fear memory engrams across 409 brain regions and supports the dispersed engram complex hypothesis through optogenetic and chemogenetic experiments.

This study identifies a hippocampal CA1 'chunking code' that represents episodes as discrete event segments and their sequential relationships, distinct from continuous spatial coding.

This study identifies a specific neuronal population in the basolateral amygdala that forms and stores fear extinction memory, showing it overlaps with reward-responsive neurons.