Heather A. Sullivan

This study uses barcoded rabies virus with single-cell and in situ sequencing to map synaptic connectivity in the mouse brain, distinguishing cortical cell types by their connectivity patterns.

The paper shows that a modified rabies virus intended for noncytotoxic neuronal tracing lost its modification due to mutations, leading to paradoxical results, and that the modified virus requires exogenous protease for efficient spread.

This study shows that cingulate cortex inputs to motor cortex are necessary for updating rule representations during sequential choice decisions after rule switches.

This paper introduces third-generation rabies viral vectors with single deletions that enable more efficient, non-toxic retrograde targeting of projection neurons compared to previous generations.

This paper introduces a non-toxic rabies virus system for long-term in vivo imaging of neuronal networks, showing minimal toxicity and normal visual response properties over 10 weeks.

The paper shows that a small number of dysregulated adult-born neurons in the hippocampus disrupt brain-wide functional connectivity and spatial memory.

The paper identifies shared and distinct transcriptomic cell types in two mouse neocortical regions using scRNA-seq, showing most excitatory types are region-specific while inhibitory types are shared.