Author

Ephraim F. Trakhtenberg

University of ConnecticutORCID 0000-0003-2844-4191Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:mouse· 3 Assay:scRNA-seq· 3 Approach:statistical model· 3 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Bruce A. RheaumeiD· 2 shared Jian Xing· 2 shared William C. TheuneiD· 2 shared Agnieszka ŁukomskaiD· 1 shared Ashiti DamaniaiD· 1 shared Juhwan KimiD· 1 shared Matthew P. FrostiD· 1 shared Muhammad S. SajidiD· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 21 mutual co-author links

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2 shared papersNeuroscience

Bruce A. RheaumeORCID

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3 papers

Recent·Most cited

Transcriptomic profiling of retinal cells reveals a subpopulation of microglia/macrophages expressing Rbpms and Spp1 markers of retinal ganglion cells (RGCs) that confound identification of RGCs

William C. Theune, Matthew P. Frost, Ephraim F. Trakhtenberg

The paper identifies Rbpms+ and Spp1+ microglia/macrophages in scRNA-seq data that mimic RGC markers, confounding RGC identification and proposes solutions to address this issue.

Brain Research · Jul 1, 2023Peer-reviewedNeuroscience

Post-injury born oligodendrocytes integrate into the glial scar and inhibit growth of regenerating axons by premature myelination

Jian Xing, Bruce A. Rheaume, Juhwan Kim, Agnieszka Łukomska, Muhammad S. Sajid, Ashiti Damania, Ephraim F. Trakhtenberg

The paper investigates how post-injury born oligodendrocytes integrate into the glial scar and inhibit axon regeneration by premature myelination.

Development · Mar 27, 2023Peer-reviewedNeuroscience

CellTools algorithm for mapping scRNA-seq query cells to the reference dataset improves the classification of resilient and susceptible retinal ganglion cell types

Bruce A. Rheaume, Jian Xing, William C. Theune, Samantha DeRosa, Ephraim F. Trakhtenberg

The paper introduces CellTools, an algorithm that improves scRNA-seq cell mapping and classification, revealing new insights into retinal ganglion cell resilience to injury.

bioRxiv · Oct 15, 2021 · PreprintBioinformatics