Author

Zhou Zhou

Cornell UniversityORCID 0000-0003-2856-7116Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 3 Approach:experimental assay· 3 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

Haiyuan YuiD· 3 shared John T. LisiD· 3 shared Abdullah OzeriD· 2 shared Alden King-Yung LeungiD· 2 shared Yiyang Jin· 2 shared Albert Li· 1 shared Alejandro BarreraiD· 1 shared Avery Willis· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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3 shared papersGenomics

Haiyuan YuORCID

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3 papers

Recent·Most cited

GenomicsCellPeer-reviewedJul 17, 2026

Robust regulatory interplay of enhancers, facilitators, and promoters in a native chromatin context

Zhou Zhou, Yang Cheng, Jaret Lieberth…·John T. Lis

The paper investigates enhancer-promoter interactions in a native chromatin context, revealing transcription factor synergy and the role of facilitators and repressive promoters in regulating gene activation.

7 citationstop 2%

humanChIP-seq

𝕏 PostBluesky

Molecular BiologybioRxivPreprintFeb 18, 2026

Molecular features underlying functional and structural interactions between diverse transcription regulatory elements in a chromosomal context

Yiyang Jin, Yuko Hasegawa, Zhou Zhou…·John T. Lis

The paper introduces CIERA-seq to study transcription regulatory element interactions and finds pdTREs and edTREs have distinct functional and chromatin features.

DOI 10.64898/2026.02.16.706221

ChIP-seqexperimental assay

𝕏 PostBluesky

GenomicsGenome biologyPeer-reviewedNov 3, 2025

Comprehensive Evaluation of Diverse Massively Parallel Reporter Assays to Functionally Characterize Human Enhancers Genome-wide

Junke Zhang, Alden King-Yung Leung, Yutong Zhu…·Haiyuan Yu

This study evaluates multiple MPRA and STARR-seq datasets to identify enhancers, finding inconsistencies due to technical factors and proposing a unified pipeline to improve cross-assay agreement.

6 citations

humanDNA methylation

𝕏 PostBluesky