Author

Yiyang Jin

Cornell University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 2 Molecular Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:ChIP-seq· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Haiyuan YuiD· 3 shared John T. LisiD· 3 shared Abdullah OzeriD· 2 shared Alden King-Yung LeungiD· 2 shared Zhou ZhouiD· 2 shared Albert Li· 1 shared Anastasiya Sushkova· 1 shared Christopher H. EmfingeriD· 1 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersGenomics

Haiyuan YuORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Robust regulatory interplay of enhancers, facilitators, and promoters in a native chromatin context

Zhou Zhou, Yang Cheng, Jaret Lieberth, Junke Zhang, Yiyang Jin, Albert Li, Haiyuan Yu, Abdullah Ozer, John T. Lis

The paper investigates enhancer-promoter interactions in a native chromatin context, revealing transcription factor synergy and the role of facilitators and repressive promoters in regulating gene activation.

Cell · Jul 17, 2026Peer-reviewedGenomics

A graph-based learning approach to predict the effects of gene perturbations on molecular phenotypes

Yiyang Jin, Yuriy Sverchkov, Anastasiya Sushkova, Michael Ohtake, Christopher H. Emfinger, Mark Craven

This paper introduces a graph-based machine learning approach to predict gene perturbation effects on molecular phenotypes using existing experimental data and biological networks.

bioRxiv · Mar 25, 2026 · PreprintSystems Biology

Molecular features underlying functional and structural interactions between diverse transcription regulatory elements in a chromosomal context

Yiyang Jin, Yuko Hasegawa, Zhou Zhou, J T Lin, Alden King-Yung Leung, Haiyuan Yu, John T. Lis

The paper introduces CIERA-seq to study transcription regulatory element interactions and finds pdTREs and edTREs have distinct functional and chromatin features.

bioRxiv · Feb 18, 2026 · PreprintMolecular Biology

Simultaneous measurement of intrinsic promoter and enhancer potential reveals principles of functional duality and regulatory reciprocity

Mauricio I. Paramo, Alden King-Yung Leung, Sagar R. Shah, Junke Zhang, Nathaniel D. Tippens, Jin Hua Liang, Yao Li, Yiyang Jin, Xiuqi Pan, Abdullah Ozer, John T. Lis, Haiyuan Yu

The paper develops a dual reporter assay to measure promoter and enhancer potential, finding that they share regulatory logic and can function reciprocally.

bioRxiv · Mar 14, 2025 · PreprintGenomics