Author

Taryn Audrey Liu

University of California, IrvineORCID 0000-0003-2863-3435Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:ChIP-seq· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Cindy X. CheniD· 2 shared Ethan W. HollingsworthiD· 2 shared Evgeny Z. KvoniD· 2 shared Sandra H. JacintoiD· 2 shared Joshua A. AlcantaraiD· 1 shared Zhuoxin CheniD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

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6 top collaborators · 14 mutual co-author links

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2 shared papersGenomics

Cindy X. ChenORCID

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2 papers

Recent·Most cited

GenomicsbioRxivPreprintJun 20, 2025

Enhancer Poising Enables Pathogenic Gene Activation by Noncoding Variants

Ethan W. Hollingsworth, Zhuoxin Chen, Cindy X. Chen…·Evgeny Z. Kvon

The paper shows that poised enhancers are susceptible to non-coding variants causing gene activation and disease, using the ZRS and autism-associated variants as examples.

DOI 10.1101/2025.06.20.660819

mouseChIP-seq

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GenomicsNature CommunicationsPeer-reviewedJan 6, 2025

Rapid and Quantitative Functional Interrogation of Human Enhancer Variant Activity in Live Mice

Ethan W. Hollingsworth, Taryn Audrey Liu, Joshua A. Alcantara…·Evgeny Z. Kvon

This paper introduces dual-enSERT, a tool for rapidly measuring enhancer variant activity in live mice, and shows it can identify shared genetic mechanisms in non-coding variant pathogenesis.

11 citations

mouseexperimental assay

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