Author

Chris J. O’Callaghan

Queen's UniversityORCID 0000-0003-2896-666XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1 Approach:statistical model· 1

Frequent Co-Authors

Dongsheng TuiD· 1 shared Geoffrey LiuiD· 1 shared Wei XuiD· 1 shared Yangqing DengiD· 1 shared

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2023-2023 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperGenetics

Dongsheng TuORCID

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1 paper

Recent·Most cited

GeneticsStatistical Methods in Medical ResearchPeer-reviewedJun 20, 2023

Two-Stage Multivariate Mendelian Randomization on Multiple Outcomes with Mixed Distributions

Yangqing Deng, Dongsheng Tu, Chris J. O’Callaghan…·Wei Xu

The paper introduces a two-stage multivariate Mendelian Randomization method to analyze mixed distributed outcomes with instrumental variables, showing improved statistical power in simulations and a clinical trial.

18 citations

GWAS summary statisticsstatistical model

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