Author

Dongsheng Tu

Queen's UniversityORCID 0000-0003-4842-2184Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:differential expression· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1 Organism:human· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Belinda Jane YeoiD· 1 shared Benjamin J. AinscoughiD· 1 shared Catrina C. FronickiD· 1 shared Chris J. O’CallaghaniD· 1 shared Christopher A. MilleriD· 1 shared David E. LarsoniD· 1 shared David K. Voduc· 1 shared Elaine R. MardisiD· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperGenomics

Belinda Jane YeoORCID

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2 papers

Recent·Most cited

GeneticsStatistical Methods in Medical ResearchPeer-reviewedJun 20, 2023

Two-Stage Multivariate Mendelian Randomization on Multiple Outcomes with Mixed Distributions

Yangqing Deng, Dongsheng Tu, Chris J. O’Callaghan…·Wei Xu

The paper introduces a two-stage multivariate Mendelian Randomization method to analyze mixed distributed outcomes with instrumental variables, showing improved statistical power in simulations and a clinical trial.

18 citations

GWAS summary statisticsstatistical model

𝕏 PostBluesky

GenomicsNature CommunicationsPeer-reviewedAug 22, 2018

The prognostic effects of somatic mutations in ER-positive breast cancer

Obi L. Griffith, Nicholas C. Spies, Meenakshi Anurag…·Matthew J. Ellis

The paper identifies somatic mutations with prognostic effects in ER+ breast cancer using genomic data from multiple cohorts.

130 citationstop 5%

humanwhole-exome sequencing

𝕏 PostBluesky