Cell BiologyProceedings of the National Academy of SciencesPeer-reviewed
Pancreatic δ-cells are resistant to auto- and paracrine inhibition in human type-2 diabetes
Muhmmad Omar‐Hmeadi, Lina Matuseviciene, Liangwen Liu…·Sebastian Barg
The paper investigates δ-cell function in type-2 diabetes, finding that these cells become resistant to inhibition, leading to hyperactivity and impaired glucose control.
DOI 10.1073/pnas.2601168123